Emily E. Noble

Education

Research

Dr. Noble's research uses rodent models to investigate how the brain controls feeding behavior and energy balance. Our research also investigates the mechanisms by which nutrition affects the brain and cognitive function. Visit the Nutritional Neuroscience Laboratory or noblelab-uga.com/ to learn more.

Teaching

Nutrition and Neuroscience FDNS 8240 (offered in the Spring, every other year)

Food and Nutritional Biochemistry FDNS/FDST 8150

Introduction to Foods and Nutrition FDNS 2100 and 2100E

Graduate Seminar in Nutritional Sciences 6900 and 8900 (Fall semester)

Prior Professional Positions

Awards

Editorial Appointments

Service

Current Research

Current research topics in include:

Determining signaling pathways in the brain that regulate eating and drinking behaviors 

Understanding how the brain regulates body weight and underlying causes of obesity

Determining the mechanistic impact of consuming a Western Diet (high fat and high sugar) on learning and memory function

Investigating the impact of adolescent nutrition on brain development and behavior

Journal Articles

Recent works- last 5 years (for full bibliography go to https://www.ncbi.nlm.nih.gov/myncbi/emily.noble.1/bibliography/public/

* Indicates co-corresponding

1. Spaulding, MO., Hoffman, JR., Madu GC., Lord, MN., Soares Iizuka, CS., Myers, KP., Noble EE., “Adolescent food insecurity in female rodents and susceptibility to diet-induced obesity” Physiol Behav.; 2023, Nov 22
2. Heo J., Schifino AG., McFaline-Figueroa J., Miller DL., Hoffman JR., Noble EE., Greising SM., Call JA., “Differential effects of Western Diet and traumatic muscle injury on skeletal muscle metabolic regulation in male and female mice. J Cachexia Sarcopenia Muscle. 2023 Oct 25; (PMID 37879629)
3. Subramanian KS., Tierno Lauer L., Hayes AMR., Décarie-Spain L., McBurnett K., Nourbash AC., Donohue KN., Kao AE., Bashaw AG., Burdakov D., Noble EE., Schier LA., Kanoski SE., “Hypothalamic melanin-concentrating hormone neurons integrate food-motivated appetitive and consummatory processes in rats” Nature Communications; 2023, March 29; 14(1):1755; (PMID 36990984)
4. Heo J., Noble EE., Call JA., “The role of exerkines on brain mitochondria: a mini-review” J Appl Physiol., 2023 Jan 1; (PMID 36417200)
5. Noble EE., “Behavioral consequences of a rumbling tummy:  fasting alters emotional state via the vagus nerve” Biological Psychiatry (invited commentary), 2022 Nov. 1
6. Tsan L., Chometton S., Hayes AMR., Klug ME., Zuo Y., Sun S., Bridi L., Lan R., Fodor AA., Noble EE., Yang X., *Kanoski SE., *Schier LA. “Early life low calorie sweetener consumption disrupts glucose regulation, sugar-motivated behavior, and memory functions in rats” JCI Insight, 2022; (PMID 36546482)
7. Décarie-Spain L., Liu CM., Tierno Lauer L., Subramanian K., Bashaw AG., Klug ME., Gianatiempo IH., Suarez AN., Noble EE., Donohue KN., Cortella AM., Hahn JD., Davis EA., Kanoski SE., “Ventral Hippocampus-Lateral Septum circuitry promotes foraging-related memory” Cell Reports, 2022; Sept. 27 (PMID 36170832)
8. McFaline-Figueroa J., Schifino AG., Nichenko AS., Lord MN., Hunda ET., Winders EA., Noble EE., Greising SM., Call JA., “Pharmaceutical agents for contractile-metabolic dysfunction after volumetric muscle loss” Tissue Engineering Part A., 2022; Aug. 1 (PMID 35620911)
9. Olszewski PK., Noble EE., Paiva L., Ueta Y., Blevins JE., “Oxytocin as a potential pharmacological tool to prevent obesity.” Journal of Neuroendocrinology, 2022; Feb. 12; e13106. (PMID 35192207)
10. Lord MN., Heo JW. Schifino AG., Hoffman, JR., Donohue KN., Call JA., Noble EE., “Sexually dimorphic effects of a Western Diet on brain mitochondrial bioenergetics and neurocognitive function.” Nutrients, 2021; 13(12), 4222. (PMID 34959774)
11. Liu, CM., Spaulding MO., Rea JJ., Noble EE.*, Kanoski SE.*, “Oxytocin and food intakecontrol: Neural, Behavioral, and Signaling Mechanisms.” IJMS, 2021; Oct. 8; 22(19): 10859 PMID 34639199
12. Tsan L., Sun S., Bridi L., Chirala L., Noble EE., Fodor, A., Kanoski SE., “Early life Western diet-induced memory impairments and gut microbiome changes in female rats are long lasting despite healthy dietary intervention.” Nutritional Neuroscience, 2021; Sept. 27:1-17; PMID 34565305
13. Noble EE., Olson, CA., Davis E., Tsan, L., Chen YW., Schade R., Liu CM., Suarez AN., Jones RB., de La Serre, C., Yang X., Hsiao EY., and Kanoski SE. “Gut microbial taxa elevated by dietary sugar disrupt memory function” Translational Psychiatry, 2021; Mar 31; 11(1):194 PMID: 33790226
14. Tsan, L., Decarie-Spain, L., Noble EE.*, Kanoski SE.* “Western diet consumption during development: setting the stage for neurocognitive dysfunction” Frontiers in Neuroscience 2021; 15:632312, PMID 33642988
15. Lord, MN., Subramanian K., Kanoski SE.*, Noble EE.* “Melanin-concentrating hormone and food intake control: neural pathways and mechanisms” Peptides 2021; Mar; 137:170476, PMID: 33370567
16. Reed DR., Alhadeff AL., Beauchamp GK., Chaudhari N., Duffy VB., Dus M., Fontanini A., Glendinning JI., Green BG., Joseph PV., Kyriazis GA., Lyte M., Maruvada P., McGann JP., McLaughlin JT., Moran TH., Murphy C., Noble EE., Pepino MY., Pluznick JL., Rother KI., Saez E., Spector AC., Sternini C., and Mattes RD., "Perspective: Sensory Nutrition and Disease." American Journal of Clinical Nutrition 2020; epub ahead of print PMID 33300030
17. Terrill SJ., Subramanian K., Lan R. Liu CM., Cortella AM., Kanoski SK.*, Noble EE.*
18. Nucleus accumbens melanin-concentrating hormone signaling promotes feeding in a sex-specific manner” Neuropharmacology 2020 Nov 1; 178:108270; PMID 32795460
18. Liu CM., Davis, EA., Suarez, AS., Wood RI., *Kanoski SE, *Noble EE., “Sex differences and estrous influences on oxytocin control of food intake” Neuroscience 2020; Nov 1; 447:63-73; PMID 31738883
19. Liu CM., Hsu TM., Suarez AN., Subramanian KS., Fatemi RA., Cortella AM., Noble EE., Roitman MF., Kanoski SE. “Central oxytocin signaling inhibits food reward-motivated behaviors and VTA dopamine responses to food-predictive cues” Hormones and Behavior 2020 Oct 1; 126:104885; PMID 32991888
20. Suarez AN., Liu CM., Cortella AM., Noble EE., Kanoski SE. “Ghrelin and orexin interact to increase meal size through a descending hippocampus to hindbrain signaling pathway” Biol Psychiatry 2020 Jun 1; 87(11): 1001-1011; PMID 31836175
21. Noble EE., Wang Z., Liu CM., Davis EA., Suarez AN., Stein LM., Tsan L., Terrill SJ., Hsu TM., Jung A., Raycraft LM., Hahn JD., Darvas M., Cortella AM., Schier LA., Johnson AW., Hayes MR., Holschneider DP., Kanoski SE. “Hypothalamus-hippocampus circuitry regulates impulsivity via melanin-concentrating hormone” Nature Communications 2019; 10(1):4923; PMID 31664021
22. Suarez A., Noble EE., Kanoski S. “Regulation of memory by feeding-relevant biological systems: following the breadcrumbs to the hippocampus” Frontiers in Molecular Neuroscience 2019; 12:101 PMID 31057368
23. Noble EE., Hsu TM., Liang J., Kanoski SE. “Early life sugar consumption has long-term negative effects on memory function in Male rats” Nutritional Neuroscience 2019; 1-11; PMID 28944721